Barrett Lab @ University of Helsinki
Finding disease endotypes via machine learning on multiomic data from biobanks
Our main research aim is to discover, understand, and measure mechanistically meaningful subtypes of a range of diseases. We believe this requires a change from characterizing diseases not by their observed clinical phenotype, but by their molecular and biological endotype. This term, coined about asthma in 2008, incorporates the need to discover both these disease subtypes themselves as well as routinely measurable, actionable biomarkers of those subtypes that can guide better treatment for patients.
We are based at the ELLIS Institute Finland, the Institute for Molecular Medicine Finland (FIMM), and the Faculty of Medicine at the University of Helsinki. This environment combines advantages of a new national research initiative into the fundamentals of applied AI with biobank-scale genomic research and the clinical reach of Finland's largest academic medical center.
News
- October 2026Apply for a PhD position in the lab as part of the ELLIS Initiative EU-wide call. Deadline 31 October.
- September 2026Profile of Jeff on the University of Helsinki webiste
- September 2026The lab
iswas recruiting PhD students and postdocs as part of the ELLIS open call. - August 2026The lab is open!
Recent posts
All →- How we use AI
Principles for LLM tool use in the Barrett Lab
- Using the drugs we have more effectively
The readout of the PROFILE trial after 5 years shows dramatic benefit from top-down treatment for Crohn's disease.
- Nordic EMBL partnership meeting 2026
Every year, researchers from national molecular medicine institutes in Finland, Denmark, Sweden and Norway meet to exchange scientific ideas.